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Herbsmith Rx Xue Fu Zhu Yu San is a classical Chinese herbal formula recommended by holistic veterinarians to support blood circulation, resolve blood stasis, and promote the smooth flow of liver qi in dogs, cats, and horses. Based on the traditional formula Xue Fu Zhu Yu Tang (also known as Drive out Stasis in the Mansion of Blood Powder, Blood's Mansion, Blood's Palace, and Persica and Carthamus Combination), it invigorates the blood, disperses blood stasis, spreads the qi of the liver, and unblocks the channels. Xue Fu Zhu Yu San is well suited for pets presenting with blood stasis patterns in the chest or thoracic region, including signs such as chest tightness, restlessness, chronic stagnation, reproductive irregularities arising from blood stasis, or a dark and choppy pulse. Available as a concentrated powder mixed into food; cats and dogs use the Canine Blend, while horses use the Equine/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.
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For Dogs (Canine Blend Powder):
For Cats (Canine Blend Powder): ¼ tsp twice daily, or as prescribed
For Horses (Equine/Horse Blend, 1,000 lb horse): Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase until the horse is accustomed to the taste. Most horses will readily accept the herbs in their grain.
Active Ingredients: Tao Ren (Semen Persicae), Hong Hua (Flos Carthami Tinctorii), Dang Gui (Radix Angelicae Sinensis), Chuan Xiong (Radix Ligustici Chuanxiong), Chi Shao (Radix Paeoniae Rubrae), Niu Xi (Radix Achyranthis Bidentatae), Chai Hu (Radix Bupleuri), Jie Geng (Radix Platycodi Grandiflori), Zhi Ke (Fructus Citri seu Ponciri), Sheng Di Huang (Radix Rehmanniae Glutinosae), Gan Cao (Radix Glycyrrhizae Uralensis)
Inactive Ingredient: Flaxseed
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Xue Fu Zhu Yu San is an 11-herb formula that combines blood-moving, qi-moving, blood-nourishing, and channel-opening herbs to address blood stasis in the chest comprehensively, without depleting the blood in the process:
Xue Fu Zhu Yu San contains potent blood-invigorating herbs including Tao Ren, Hong Hua, Chuan Xiong, and Chi Shao, which have significant blood-moving and anticoagulant properties. Pets currently on prescription medications should use this formula under veterinary supervision, as herb-drug interaction research in dogs and cats remains limited.
Medication categories warranting extra caution include anticoagulant or antiplatelet medications, non-steroidal anti-inflammatory drugs (NSAIDs), cardiac medications, immunosuppressive drugs, and pets managing multiple concurrent prescriptions. Your authorizing veterinarian can determine appropriateness based on your pet's condition, current medications, and laboratory results.
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In Traditional Chinese Veterinary Medicine, Xue Fu Zhu Yu San is indicated for blood stasis patterns in the chest and upper burner, presenting as chest tightness, restlessness, chronic stagnation, a dark or dusky tongue, a choppy pulse, and reproductive irregularities arising from blood stasis. It is a good alternative to Drive out Stasis in the Mansion of Blood Powder, Blood's Mansion, Blood's Palace, and Persica and Carthamus Combination, and is appropriate for pets with established blood stasis patterns rather than acute or early-stage presentations.
Mix the powder directly into food or grain at the dose recommended for your pet's species and body weight. Both dogs and cats use the Canine Blend; horses use the Equine/Horse Blend. Dogs and cats receive the formula twice daily; horses receive two tablespoons twice daily for the first 20 days, then once daily for maintenance. Your authorizing veterinarian will confirm the appropriate dose and schedule for your individual pet.
Response time varies depending on the severity and chronicity of the blood stasis pattern. Many pets show improvement in restlessness, chest tightness, and circulation-related signs within 4 to 8 weeks of consistent use. Chronic or deeply rooted blood stasis patterns may require a longer course of treatment, and your veterinarian may recommend periodic reassessment to adjust the formula or dosing as your pet responds.
Combination with complementary TCVM formulas is common in holistic veterinary practice and should be guided by your authorizing veterinarian based on your pet's full pattern diagnosis. Because this formula contains multiple potent blood-invigorating herbs with anticoagulant properties, veterinary oversight is especially important if your pet is on anticoagulants, NSAIDs, or cardiac medications, to ensure the treatment plan fits your pet's overall health status.
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