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Herbsmith Rx Gui Pi Tang is a classical Chinese herbal formula recommended by holistic veterinarians to augment the qi, tonify the blood, strengthen the spleen, and nourish the heart in dogs, cats, and horses. Also known as Restore the Spleen Powder, Ginseng and Longan Combination, Gather Vitality, and Return the Spleen Formula, this ten-herb formula from Yan Yonghe's Ji Sheng Fang (Formulas for Saving Lives, Song dynasty, 1253 CE) addresses the dual vacuity of the heart and spleen pattern through a coordinated strategy of spleen qi tonification, heart blood nourishment, and spirit calming. The formula's dual-organ focus reflects the classical TCVM understanding that the spleen is the source of qi and blood production (the post-heaven foundation of all qi and blood), and that when spleen qi vacuity fails to generate adequate qi and blood, the heart, which requires blood to nourish the spirit (shen) and qi to drive the heartbeat, becomes blood-deficient and qi-deficient simultaneously. The result is the characteristic heart-spleen dual vacuity pattern: spleen qi vacuity generates the fatigue, poor digestion, and reduced appetite from inadequate qi production; heart blood and qi vacuity generates the heart palpitations from inadequate blood and qi to nourish and drive the heart; and heart spirit disturbance from heart blood vacuity generates the anxiety, restlessness, night panting, and disturbed sleep that are the most distressing presenting signs for the pet and owner. Well suited for dogs, cats, and horses presenting with the heart-spleen dual vacuity pattern, characterized by fatigue and reduced stamina, reduced appetite and loose stools or poor digestion from spleen qi vacuity, heart palpitations or irregular heartbeat from heart qi and blood vacuity, anxiety, restlessness, and night panting from heart spirit disturbance, a pale tongue with a thin white coating reflecting the qi and blood vacuity, and a thin weak pulse reflecting the blood and qi insufficiency. Available as a concentrated powder mixed into food; cats and dogs use the Canine Blend, while horses use the Equine/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.
VETERINARY AUTHORIZATION REQUIRED: Submit Your Authorization Request or Request a TCVM Telemedicine Consultation
For Dogs (Canine Blend Powder):
For Cats (Canine Blend Powder): ¼ tsp twice daily, or as prescribed
For Horses (Equine/Horse Blend, 1,000 lb horse): Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase until the horse is accustomed to the taste. Most horses will readily accept the herbs in their grain.
Active Ingredients: Ren Shen (Radix Ginseng), Huang Qi (Radix Astragali Membranacei), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Fu Ling (Sclerotium Poriae Cocos), Suan Zao Ren (Semen Zizyphi Spinosae), Long Yan Rou (Arillus Euphoriae Longanae), Mu Xiang (Radix Aucklandiae Lappae), Zhi Gan Cao (Honey-fried Radix Glycyrrhizae Uralensis), Dang Gui (Radix Angelicae Sinensis), Zhi Yuan Zhi (Honey-fried Radix Polygalae Tenuifoliae)
Inactive Ingredient: Flaxseed
VETERINARY AUTHORIZATION REQUIRED: Submit Your Authorization Request or Request a TCVM Telemedicine Consultation
Gui Pi Tang is a ten-herb formula organized into four functional groups: a principal qi-tonifying pair (Ren Shen, Huang Qi), a spleen-strengthening support pair (Bai Zhu, Fu Ling), a heart blood-nourishing and spirit-calming group (Suan Zao Ren, Long Yan Rou, Dang Gui, Zhi Yuan Zhi), and a qi-activating and harmonizing pair (Mu Xiang, Zhi Gan Cao):
Gui Pi Tang contains Ren Shen (ginseng) with well-characterized interactions with warfarin and other anticoagulant medications (Ren Shen can either potentiate or antagonize anticoagulant effects depending on dose and formulation), MAO inhibitors (Ren Shen may cause manic-like effects in combination), and hypoglycemic medications (Ren Shen's blood glucose-lowering effects may potentiate insulin and oral hypoglycemics). Huang Qi has immunomodulatory properties that warrant monitoring in animals on cyclosporine, tacrolimus, and other immunosuppressive medications. Suan Zao Ren has mild sedative properties that may potentiate pharmaceutical sedatives, anxiolytics, benzodiazepines, phenobarbital, and other CNS depressant medications. Dang Gui has mild estrogenic properties and anticoagulant effects that compound Ren Shen's anticoagulant interaction profile and warrant caution in animals on hormonal medications. Zhi Yuan Zhi contains saponins and has mild sedative and CNS-active properties that may potentiate pharmaceutical sedatives and anxiolytics. Zhi Gan Cao at sustained doses may interact with corticosteroids, diuretics, and antihypertensive medications. The formula is a tonic formula appropriate for the heart-spleen dual vacuity pattern confirmed through tongue, pulse, and clinical assessment; it is not appropriate for excess patterns, fire or heat patterns, or presentations with significant dampness accumulation where the formula's blood-nourishing herbs would worsen the dampness.
Medication categories warranting extra caution include anticoagulant and antiplatelet medications (Ren Shen and Dang Gui), MAO inhibitors and psychoactive medications (Ren Shen, Suan Zao Ren, Zhi Yuan Zhi), hypoglycemic medications and insulin (Ren Shen), immunosuppressive medications (Huang Qi's immunomodulatory effects), pharmaceutical sedatives, anxiolytics, and anticonvulsants (Suan Zao Ren and Zhi Yuan Zhi's sedative properties), hormonal medications (Dang Gui's estrogenic properties), and corticosteroids and antihypertensives (Zhi Gan Cao at sustained doses). Your authorizing veterinarian will determine appropriateness based on your animal's condition, current medications, and confirmation of the heart-spleen dual vacuity pattern through tongue quality, pulse character, and clinical assessment of the qi vacuity, blood vacuity, and spirit disturbance presentation.
VETERINARY AUTHORIZATION REQUIRED: Submit Your Authorization Request or Request a TCVM Telemedicine Consultation
In Traditional Chinese Veterinary Medicine, Gui Pi Tang is indicated for the heart and spleen dual vacuity (xin pi liang xu) pattern, where spleen qi vacuity fails to generate adequate qi and blood, creating downstream heart qi and blood deficiency that disturbs the heart spirit. The presenting signs span two organ systems: the spleen qi vacuity generates fatigue and reduced stamina, poor appetite and digestion, and loose stools; the heart qi and blood vacuity generates heart palpitations and irregular heartbeat from insufficient blood and qi to nourish and drive the heart; and the heart spirit disturbance from heart blood vacuity generates anxiety, restlessness, night panting (particularly in dogs), and disturbed sleep. Your authorizing veterinarian will confirm the heart-spleen dual vacuity pattern through tongue assessment (pale tongue with thin coating reflecting qi and blood vacuity), pulse character (thin, weak, possibly rapid pulse reflecting blood vacuity and spirit disturbance), and differentiation from patterns that require different formulas: spleen qi vacuity without heart involvement (Si Jun Zi Tang), heart blood vacuity without spleen involvement (Tian Wang Bu Xin Dan), yin vacuity heat generating spirit disturbance (Suan Zao Ren Tang), or anxiety from liver qi stagnation constraining the heart (different approach entirely).
Mix the powder directly into food or grain at the dose recommended for your animal's species and body weight. Dogs and cats use the Canine Blend; horses use the Equine/Horse Blend. Dogs and cats receive the formula twice daily; horses receive two tablespoons twice daily for the first 20 days, then once daily for maintenance. Because Gui Pi Tang contains Ren Shen with anticoagulant, MAO inhibitor, and hypoglycemic drug interaction potential, and Suan Zao Ren and Zhi Yuan Zhi with sedative-potentiating properties, your authorizing veterinarian must review all current medications before beginning use. Gui Pi Tang is a constitutional tonification formula intended for sustained use over weeks to months; the heart-spleen dual vacuity pattern is chronic and requires consistent tonification over a full treatment course to fully restore the spleen's blood production capacity and the heart's blood and qi sufficiency.
As a constitutional qi and blood tonification formula addressing a chronic heart-spleen dual vacuity pattern, Gui Pi Tang requires a sustained treatment course to produce full therapeutic results. Early improvement in the spirit disturbance signs (reduced anxiety, less night panting, improved sleep quality) is often seen within 2 to 4 weeks as the blood-nourishing and spirit-calming herbs (Suan Zao Ren, Long Yan Rou, Zhi Yuan Zhi) begin to nourish the heart blood and calm the spirit. Meaningful improvement in spleen qi vacuity signs (improved digestion, better appetite, improved stamina and energy) typically requires 6 to 12 weeks of consistent use, as qi tonification gradually restores the spleen's blood-production capacity. Full resolution of the heart-spleen dual vacuity pattern, including normalization of the pale tongue to a pink tongue with more substance and return of the thin weak pulse to a fuller quality, typically requires 3 to 6 months of sustained use. Your authorizing veterinarian will monitor tongue and pulse quality, energy and digestion, and spirit-related signs throughout the treatment course to confirm the pattern is resolving and adjust the formula as the qi and blood are progressively restored.
In Traditional Chinese Veterinary Medicine, night panting in dogs is one of the most recognized clinical signs of heart blood vacuity with spirit disturbance, and its nocturnal character has a specific TCVM explanation. The heart spirit (shen) is anchored in the heart by the heart blood during the day; at night, when the yin is dominant and the yang qi retreats inward, the spirit should settle into the heart blood and rest. When heart blood is deficient, the spirit lacks the blood substrate needed to anchor it during the night's yin phase, and it becomes agitated and floats upward, generating the panting, restlessness, and inability to settle that owners recognize as night panting. The pattern is typically worse in the second half of the night (after midnight, when yin turns toward yang) and is often accompanied by the dog seeking human contact or pacing, reflecting the displaced spirit seeking grounding that deficient heart blood cannot provide. Gui Pi Tang addresses night panting by tonifying the spleen qi to restore blood production at the source, nourishing the heart blood through Suan Zao Ren, Long Yan Rou, and Dang Gui to rebuild the substrate the spirit requires for nighttime anchoring, and calming the spirit directly through Zhi Yuan Zhi's heart orifice-opening and spirit-settling action. As heart blood is progressively restored over the course of treatment, the spirit's nighttime anchoring capacity is rebuilt, and the night panting gradually resolves.
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Herbsmith receives certificates of analysis from independent laboratories for every batch of herbs that go into our herbal blends. This assures us that all necessary steps have been taken to ensure the quality and potency of every blend that carries the Herbsmith name and gives us the confidence to say that Herbsmith is the natural option for animal wellness.
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