Herbsmith Rx Chai Hu Shu Gan San for Cats, Dogs and Horses

{"id":6898118033478,"title":"Herbsmith Rx Chai Hu Shu Gan San for Cats, Dogs and Horses","handle":"herbsmith-rx-chai-hu-shu-gan-san-for-cats-dogs-and-horses","description":"\u003cdiv style=\"text-align: right;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0021\/2110\/5457\/files\/veterinary_authorizaton_required_for_tcvm_herbal_formulas_240x240.jpg?v=1787081808\" alt=\"Veterinary Authorization Required for TCVM Herbal Formulas - TCVM Pet Supply\" style=\"margin: 5px 5px 5px 5px; float: right;\"\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eHerbsmith Rx Chai Hu Shu Gan San is a classical Chinese herbal formula recommended by holistic veterinarians to spread liver qi, harmonize the liver and spleen, activate the blood, and address stagnation-related discomfort and rib-side tension that liver qi stagnation can cause in dogs, cats, and horses. Also known as Bupleurum and Cyperus Powder, Bupleurum Liver Soothing Pills, Bupleurum Shu Gan, and Bupleurum and Cyperus Combination, Chai Hu Shu Gan San is one of the most important classical Chinese formulas for the liver qi stagnation pattern, derived from the classical formula Si Ni San with the addition of Chuan Xiong, Chen Pi, and Xiang Fu to strengthen the qi-moving, blood-activating, and liver-coursing actions. The seven-herb formula addresses the liver qi stagnation pattern through three simultaneous therapeutic strategies: spreading the liver qi and releasing the constrained liver wood energy (Chai Hu, Xiang Fu, Zhi Ke, Chen Pi), activating the blood and harmonizing the liver to address the blood stagnation that liver qi stagnation generates over time (Chuan Xiong, Bai Shao), and harmonizing the liver and spleen while moderating the formula's moving herbs (Zhi Gan Cao). Well suited for dogs, cats, and horses presenting with the liver qi stagnation pattern, characterized by irritability, emotional tension, or behavioral changes reflecting the constrained liver qi; rib-side tension or flank sensitivity; digestive irregularities from liver-spleen disharmony; a wiry pulse reflecting liver qi constraint; and a normal or slightly dusky tongue. Available as a concentrated powder mixed into food; dogs and cats use the Canine Blend, while horses use the Equine\/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eVETERINARY AUTHORIZATION REQUIRED: \u003ca href=\"https:\/\/tcvmpet.com\/pages\/get-an-authorization\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eSubmit Your Authorization Request\u003c\/a\u003e or \u003ca href=\"https:\/\/tcvmpet.com\/pages\/schedule-a-consultation\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eRequest a TCVM Telemedicine Consultation\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eWhat It Supports\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eLiver qi spreading and constraint releasing through Chai Hu as the chief herb (25%):\u003c\/strong\u003e Spreads the liver qi, releases the constrained liver wood energy, and addresses the liver qi stagnation that is generating the formula's full pattern through Chai Hu (bupleurum root, Radix Bupleuri). Chai Hu's bitter, acrid, and slightly cold nature enters the liver and gallbladder channels to course the liver qi and lift the constrained yang of the liver wood, directly addressing the primary pathology of liver qi stagnation. As the formula's chief herb at 25%, Chai Hu provides the primary liver-coursing and qi-spreading action that underpins the entire formula's therapeutic strategy. Chai Hu has mild hepatoprotective effects due to its saikosaponin content; monitoring is warranted in animals on hepatically metabolized medications or those with pre-existing hepatic conditions, where saikosaponin's effects on hepatic enzyme activity could interact with medication metabolism.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eQi stagnation resolving and liver qi moving through Xiang Fu (19%):\u003c\/strong\u003e Moves the liver qi, resolves qi stagnation, harmonizes the middle jiao, and addresses the emotional and digestive manifestations of liver qi constraint through Xiang Fu (cyperus rhizome, Rhizoma Cyperi Rotundi). Xiang Fu's acrid, slightly bitter, and neutral nature enters the liver, triple burner, and spleen channels to move the liver qi broadly through all three burners, making it particularly effective for the full-body manifestations of liver qi stagnation that affect the emotional state, the digestive system, and the rib-side region simultaneously. Xiang Fu is one of the most important single herbs in classical materia medica for liver qi stagnation across all its manifestations. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eQi stagnation breaking and chest and rib-side opening through Zhi Ke (19%):\u003c\/strong\u003e Breaks qi stagnation, descends the qi, and opens the chest and rib-side region to relieve the tension and stagnation that liver qi stagnation generates in the chest and flank through Zhi Ke (bitter orange fruit, Fructus Citri Aurantii). Zhi Ke's bitter, acrid, and slightly cold nature enters the spleen, stomach, and large intestine channels to move and descend the stagnant qi in the middle and upper burner, addressing the rib-side tension and chest oppression that are the formula's key local manifestations of liver qi stagnation. Zhi Ke's qi-moving action complements Chai Hu and Xiang Fu's liver-coursing action by ensuring the stagnant qi is moved downward and outward as well as released from the liver channel. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eBlood activation and liver blood nourishment through Chuan Xiong (12%):\u003c\/strong\u003e Activates the blood, moves the qi, dispels wind, and addresses the blood stagnation that prolonged liver qi stagnation generates in the channels through Chuan Xiong (ligusticum rhizome, Radix Ligustici Chuanxiong). Chuan Xiong's acrid and warm nature enters the liver, gallbladder, and pericardium channels to activate the blood and move the qi simultaneously, addressing both the secondary blood stagnation that liver qi stagnation generates over time and the qi stagnation directly through the blood-qi relationship. In the formula's architecture, Chuan Xiong ensures the formula addresses both the blood and qi levels of the stagnation, preventing purely qi-moving herbs from generating heat without addressing the blood component. Antiplatelet effects from ligustilide and ferulic acid content; monitoring warranted in animals on anticoagulant medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eLiver blood nourishment and liver yin support through Bai Shao (19%):\u003c\/strong\u003e Nourishes the liver blood, softens the liver, harmonizes the liver and spleen, and moderates the formula's dispersing herbs through Bai Shao (white peony root, Radix Paeoniae Lactiflorae). Bai Shao's bitter, sour, and slightly cold nature enters the liver and spleen channels to nourish the liver blood and yin that the stagnation pattern is depleting, and to soften the liver's tendency toward constraint by nourishing the substance (blood and yin) that the liver wood requires to maintain its free coursing function. Bai Shao's presence at 19% reflects the classical principle that liver qi stagnation is always accompanied by some degree of liver blood and yin insufficiency - the constraint depletes the substance, and the substance insufficiency worsens the constraint. Generally well tolerated; mild antiplatelet effects from paeoniflorin content.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eQi moving and middle jiao harmonizing through Chen Pi:\u003c\/strong\u003e Moves the qi, dries dampness, harmonizes the middle jiao, and addresses the digestive irregularities that liver qi stagnation and liver-spleen disharmony generate through Chen Pi (tangerine peel, Pericarpium Citri Reticulatae). Chen Pi's acrid, bitter, and warm nature enters the spleen, stomach, and lung channels to move qi in the middle jiao and dry the dampness generated by liver-spleen disharmony, addressing the bloating, borborygmus, and digestive irregularity component of the liver qi stagnation pattern. Chen Pi complements the formula's liver-coursing herbs by ensuring the middle jiao qi is also moved, and the spleen's transforming function is supported alongside the liver's coursing function. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFormula harmonization and liver-spleen harmonizing through Zhi Gan Cao (6%):\u003c\/strong\u003e Harmonizes the formula's herbs, moderates the dispersing nature of the qi-moving herbs, tonifies the qi and spleen, and harmonizes the liver and spleen relationship through Zhi Gan Cao (honey-fried licorice root, Honey-fried Radix Glycyrrhizae Uralensis). The honey-fried preparation strengthens Gan Cao's qi-tonifying and spleen-harmonizing properties, making it particularly appropriate in a formula addressing liver-spleen disharmony where the spleen's qi requires support alongside the liver's qi-moving treatment. Glycyrrhizin content with mineralocorticoid-like effects; monitoring warranted with corticosteroids and antihypertensive medications in long-term use.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eTCVM Principles\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003ePrimary action - liver qi stagnation with liver-spleen disharmony through the combined strategy of spreading the liver qi and releasing constraint (Chai Hu, Xiang Fu, Zhi Ke, Chen Pi), activating the blood and nourishing the liver (Chuan Xiong, Bai Shao), and harmonizing the liver and spleen while moderating the formula's moving herbs (Zhi Gan Cao):\u003c\/strong\u003e Addresses the liver qi stagnation pattern through three simultaneous therapeutic strategies. Chai Hu courses the liver qi and releases the constrained liver wood directly; Xiang Fu moves the liver qi through all three burners; Zhi Ke opens the chest and rib-side and descends the stagnant qi; Chen Pi moves the middle jiao qi and harmonizes the spleen. Chuan Xiong activates the blood and addresses the secondary blood stagnation; Bai Shao nourishes the liver blood and yin to address the substance component of the constraint. Zhi Gan Cao harmonizes the liver and spleen and moderates the formula's dispersing action. Treatment Principles: spread the liver qi, harmonize the liver and spleen, activate the blood, and address rib-side tension and stagnation-related discomfort.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eSecondary action - pattern differentiation from liver fire (requiring stronger heat-clearing herbs), liver blood vacuity without qi stagnation (requiring blood-nourishing formulas without the strong qi-moving emphasis), and liver yang rising (requiring descending and anchoring herbs):\u003c\/strong\u003e Chai Hu Shu Gan San is indicated specifically for the liver qi stagnation pattern with liver-spleen disharmony, not for liver fire (which requires cold-clearing herbs and less acrid dispersing action), liver blood vacuity without significant qi stagnation (where the formula's strong qi-moving herbs could further deplete the blood), or liver yang rising (which requires descending and anchoring strategies). Clinical differentiation centers on the wiry pulse, behavioral and emotional signs of constraint (irritability, restlessness, tension), rib-side and flank sensitivity, and digestive signs of liver-spleen disharmony without significant heat signs. Your authorizing veterinarian will confirm the liver qi stagnation pattern through tongue and pulse examination, along with behavioral and clinical assessment.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eAvailable Forms\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003ePowder - Canine Blend (for dogs and cats):\u003c\/strong\u003e Available in 75 g, 150 g, 500 g, 900 g, and 1200 g sizes; mix into food at the recommended dose for your pet's weight. Cats and dogs both use this blend.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003ePowder - Equine\/Horse Blend (for horses):\u003c\/strong\u003e Available in 150 g, 500 g, 900 g, and 1200 g sizes; mix into grain at the recommended dose for your horse.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eSuggested Use\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFor Dogs (Canine Blend Powder):\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eUnder 30 lbs: ½ tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e30-80 lbs: 1 tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e80-120 lbs: 1½ tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eOver 120 lbs: 2 tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFor Cats (Canine Blend Powder):\u003c\/strong\u003e ¼ tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFor Horses (Equine\/Horse Blend, 1,000 lb horse):\u003c\/strong\u003e Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase. Most horses will readily accept the herbs in their grain.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eIngredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eActive Ingredients:\u003c\/strong\u003e Chai Hu (Radix Bupleuri) (25%), Bai Shao (Radix Paeoniae Lactiflorae) (19%), Xiang Fu (Rhizoma Cyperi Rotundi) (19%), Zhi Ke (Fructus Citri Aurantii) (19%), Chuan Xiong (Radix Ligustici Chuanxiong) (12%), Zhi Gan Cao (Honey-fried Radix Glycyrrhizae Uralensis) (6%), Chen Pi (Pericarpium Citri Reticulatae)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eInactive Ingredient:\u003c\/strong\u003e Flaxseed\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eVETERINARY AUTHORIZATION REQUIRED: \u003ca href=\"https:\/\/tcvmpet.com\/pages\/get-an-authorization\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eSubmit Your Authorization Request\u003c\/a\u003e or \u003ca href=\"https:\/\/tcvmpet.com\/pages\/schedule-a-consultation\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eRequest a TCVM Telemedicine Consultation\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eActive Ingredient TCVM Actions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eChai Hu Shu Gan San is a seven-herb formula organized around three therapeutic strategies: liver qi spreading and constraint releasing (Chai Hu, Xiang Fu, Zhi Ke, Chen Pi), blood activation and liver nourishment (Chuan Xiong, Bai Shao), and liver-spleen harmonization (Zhi Gan Cao): \u003c\/span\u003e\u003c\/p\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eChai Hu (Radix Bupleuri) - Bupleurum Root:\u003c\/strong\u003e Chief herb; spreads the liver qi and releases liver qi constraint directly. Saikosaponin content with hepatic enzyme activity effects; monitoring warranted with hepatically metabolized medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eBai Shao (Radix Paeoniae Lactiflorae) - White Peony Root:\u003c\/strong\u003e Nourishes the liver blood and yin, softens the liver, and harmonizes the liver and spleen; addresses the blood and yin insufficiency component of the constraint pattern. Mild antiplatelet effects from paeoniflorin.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eXiang Fu (Rhizoma Cyperi Rotundi) - Cyperus Rhizome:\u003c\/strong\u003e Moves the liver qi through all three burners; addresses the full-body manifestations of liver qi stagnation. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eZhi Ke (Fructus Citri Aurantii) - Bitter Orange Fruit:\u003c\/strong\u003e Breaks qi stagnation, descends the qi, and opens the chest and rib-side; addresses the local manifestations of liver qi stagnation in the thorax and flank. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eChuan Xiong (Radix Ligustici Chuanxiong) - Ligusticum Root \/ Szechuan Lovage Root:\u003c\/strong\u003e Activates the blood and moves the qi; addresses the secondary blood stagnation that liver qi stagnation generates. Antiplatelet effects from ligustilide and ferulic acid; monitoring warranted with anticoagulant medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eZhi Gan Cao (Honey-fried Radix Glycyrrhizae Uralensis) - Honey-Fried Licorice Root:\u003c\/strong\u003e Harmonizes the formula, tonifies the qi and spleen, and moderates the dispersing herbs; strengthened spleen-tonifying action from honey-frying. Glycyrrhizin content; monitoring warranted with corticosteroids and antihypertensive medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eChen Pi (Pericarpium Citri Reticulatae) - Tangerine Peel \/ Aged Citrus Peel:\u003c\/strong\u003e Moves the middle jiao qi and dries dampness; addresses the digestive and spleen component of liver-spleen disharmony. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003ePotential Drug Interactions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eChai Hu Shu Gan San has a moderate drug interaction profile. The primary concern is Chai Hu's saikosaponin content, which affects hepatic cytochrome P450 enzyme activity and can alter the metabolism of medications processed by these pathways, warranting veterinary review of all hepatically metabolized medications before use. Secondary concerns include Chuan Xiong's ligustilide and ferulic acid antiplatelet effects (monitoring warranted in animals on anticoagulant or antiplatelet medications, where the combined blood-activating effect of Chuan Xiong and Bai Shao could compound the medication's effects); Zhi Gan Cao's glycyrrhizin-based mineralocorticoid-like effects (monitoring warranted with corticosteroids, where additive effects on fluid retention and electrolytes are possible, and antihypertensive medications, where the fluid-retaining tendency could counteract the medication); and Bai Shao's paeoniflorin antiplatelet effects (mild, but additive with Chuan Xiong in animals on anticoagulant medications).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eMedication categories warranting extra caution: hepatically metabolized medications subject to CYP enzyme interactions (Chai Hu saikosaponin effects - primary concern), anticoagulant and antiplatelet medications (Chuan Xiong and Bai Shao combined antiplatelet effects), corticosteroids (Zhi Gan Cao glycyrrhizin additive mineralocorticoid effects), and antihypertensive medications (Zhi Gan Cao fluid-retaining tendency). Your authorizing veterinarian will determine appropriateness based on your animal's condition, current medications, and confirmation of the liver qi stagnation pattern through tongue quality, pulse character, and behavioral and clinical assessment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eVETERINARY AUTHORIZATION REQUIRED: \u003ca href=\"https:\/\/tcvmpet.com\/pages\/get-an-authorization\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eSubmit Your Authorization Request\u003c\/a\u003e or \u003ca href=\"https:\/\/tcvmpet.com\/pages\/schedule-a-consultation\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eRequest a TCVM Telemedicine Consultation\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eFrequently Asked Questions\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eWhat conditions is Chai Hu Shu Gan San used for in TCVM?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eIn Traditional Chinese Veterinary Medicine, Chai Hu Shu Gan San is indicated for the liver qi stagnation pattern with liver-spleen disharmony. The clinical presentation centers on irritability, emotional tension, or behavioral changes reflecting constrained liver wood energy; rib-side or flank sensitivity; digestive irregularities including bloating, borborygmus, or alternating loose and firm stools from liver-spleen disharmony; and a wiry pulse reflecting constrained liver qi. The formula is particularly well suited for animals whose liver qi stagnation has a clear behavioral or emotional component alongside the physical signs, and for cases where rib-side tension and digestive irregularity coexist as the primary presentation. Your authorizing veterinarian will confirm the liver qi stagnation pattern through tongue and pulse examination, along with behavioral and clinical assessment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eHow is Chai Hu Shu Gan San administered to dogs, cats, and horses?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eMix the powder into food or grain at the dose recommended for your animal's species and body weight. Dogs and cats use the Canine Blend; horses use the Equine\/Horse Blend. All species receive the formula twice daily, with horses following the standard 20-day twice-daily loading protocol before transitioning to once-daily maintenance dosing. Because Chai Hu Shu Gan San contains Chai Hu with potential hepatic enzyme interactions, veterinary review of all current medications is important before use. The formula's qi-moving and blood-activating herbs make veterinary monitoring appropriate in animals on anticoagulant medications.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eHow long does it take to see results with Chai Hu Shu Gan San?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eBecause it addresses qi stagnation rather than deep constitutional vacuity, Chai Hu Shu Gan San typically shows relatively early improvement in the most responsive signs. Early improvement in behavioral signs of liver qi constraint (reduced irritability, decreased tension, improved emotional ease) and rib-side sensitivity may appear within 1 to 3 weeks as the formula's liver-coursing and qi-moving herbs begin addressing the stagnation. Improvement in the wiry pulse quality and digestive normalization typically requires 3 to 6 weeks. Chronic liver qi stagnation with established liver-spleen disharmony may require 2 to 3 months of treatment before the pattern is meaningfully resolved. Your authorizing veterinarian will monitor pulse quality, behavioral signs, and digestive function throughout the treatment course.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eCan Chai Hu Shu Gan San be combined with other herbal formulas?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eChai Hu Shu Gan San is sometimes used alongside other formulas when the liver qi stagnation pattern coexists with additional patterns requiring treatment, but all formula combinations require veterinary authorization and supervision. Common clinical scenarios where combination is considered include liver qi stagnation with underlying liver blood vacuity (where a blood-nourishing formula may be added), liver qi stagnation with heat signs that the formula's mild cold-natured herbs cannot address alone, or liver-spleen disharmony with significant spleen qi vacuity requiring additional spleen support. Because the formula's qi-moving and blood-activating herbs can interact with each other and with other formulas' blood-moving herbs, a comprehensive veterinary review of all formulas and medications used together is required before initiating any combination.\u003c\/span\u003e\u003c\/p\u003e","published_at":"2022-05-20T18:01:55-05:00","created_at":"2022-04-28T12:09:44-05:00","vendor":"Herbsmith Rx","type":"Pet Vitamins \u0026 Supplements","tags":["Herb Type_Powder","Product_Type_Herb","Species_Cat","Species_Dog","Species_Horse","Vendor_Herbsmith_Rx"],"price":7000,"price_min":7000,"price_max":22200,"available":true,"price_varies":true,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":40018645614662,"title":"Powder - Canine Blend \/ 75 g Powder","option1":"Powder - Canine Blend","option2":"75 g Powder","option3":null,"sku":"HHSC-75","requires_shipping":true,"taxable":true,"featured_image":{"id":29685060894790,"product_id":6898118033478,"position":2,"created_at":"2022-10-08T07:11:36-05:00","updated_at":"2022-10-08T09:32:54-05:00","alt":"Herbsmith Rx Chai Hu Shu Gan San for Cats, Dogs and Horses Herbal Powder","width":960,"height":997,"src":"\/\/tcvmpet.com\/cdn\/shop\/products\/herbsmith3_969x997px_59d0d5bb-d4d9-46d2-9732-0feaa911e7c0-sw.jpg?v=1665239574","variant_ids":[40018645614662]},"available":true,"name":"Herbsmith Rx Chai Hu Shu Gan San for Cats, Dogs and Horses - Powder - Canine Blend \/ 75 g Powder","public_title":"Powder - Canine Blend \/ 75 g Powder","options":["Powder - Canine Blend","75 g Powder"],"price":7000,"weight":75,"compare_at_price":null,"inventory_management":null,"barcode":"850000022386","featured_media":{"alt":"Herbsmith Rx Chai Hu Shu Gan San for Cats, Dogs and Horses Herbal Powder","id":21966532804678,"position":2,"preview_image":{"aspect_ratio":0.963,"height":997,"width":960,"src":"\/\/tcvmpet.com\/cdn\/shop\/products\/herbsmith3_969x997px_59d0d5bb-d4d9-46d2-9732-0feaa911e7c0-sw.jpg?v=1665239574"}},"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":40018645647430,"title":"Powder - Canine Blend \/ 150 g Powder","option1":"Powder - Canine Blend","option2":"150 g Powder","option3":null,"sku":"HHSC-150","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Herbsmith Rx Chai Hu Shu Gan San for Cats, Dogs and Horses - Powder - Canine Blend \/ 150 g Powder","public_title":"Powder - 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TCVM Pet Supply\" style=\"margin: 5px 5px 5px 5px; float: right;\"\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eHerbsmith Rx Chai Hu Shu Gan San is a classical Chinese herbal formula recommended by holistic veterinarians to spread liver qi, harmonize the liver and spleen, activate the blood, and address stagnation-related discomfort and rib-side tension that liver qi stagnation can cause in dogs, cats, and horses. Also known as Bupleurum and Cyperus Powder, Bupleurum Liver Soothing Pills, Bupleurum Shu Gan, and Bupleurum and Cyperus Combination, Chai Hu Shu Gan San is one of the most important classical Chinese formulas for the liver qi stagnation pattern, derived from the classical formula Si Ni San with the addition of Chuan Xiong, Chen Pi, and Xiang Fu to strengthen the qi-moving, blood-activating, and liver-coursing actions. The seven-herb formula addresses the liver qi stagnation pattern through three simultaneous therapeutic strategies: spreading the liver qi and releasing the constrained liver wood energy (Chai Hu, Xiang Fu, Zhi Ke, Chen Pi), activating the blood and harmonizing the liver to address the blood stagnation that liver qi stagnation generates over time (Chuan Xiong, Bai Shao), and harmonizing the liver and spleen while moderating the formula's moving herbs (Zhi Gan Cao). Well suited for dogs, cats, and horses presenting with the liver qi stagnation pattern, characterized by irritability, emotional tension, or behavioral changes reflecting the constrained liver qi; rib-side tension or flank sensitivity; digestive irregularities from liver-spleen disharmony; a wiry pulse reflecting liver qi constraint; and a normal or slightly dusky tongue. Available as a concentrated powder mixed into food; dogs and cats use the Canine Blend, while horses use the Equine\/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eVETERINARY AUTHORIZATION REQUIRED: \u003ca href=\"https:\/\/tcvmpet.com\/pages\/get-an-authorization\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eSubmit Your Authorization Request\u003c\/a\u003e or \u003ca href=\"https:\/\/tcvmpet.com\/pages\/schedule-a-consultation\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eRequest a TCVM Telemedicine Consultation\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eWhat It Supports\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eLiver qi spreading and constraint releasing through Chai Hu as the chief herb (25%):\u003c\/strong\u003e Spreads the liver qi, releases the constrained liver wood energy, and addresses the liver qi stagnation that is generating the formula's full pattern through Chai Hu (bupleurum root, Radix Bupleuri). Chai Hu's bitter, acrid, and slightly cold nature enters the liver and gallbladder channels to course the liver qi and lift the constrained yang of the liver wood, directly addressing the primary pathology of liver qi stagnation. As the formula's chief herb at 25%, Chai Hu provides the primary liver-coursing and qi-spreading action that underpins the entire formula's therapeutic strategy. Chai Hu has mild hepatoprotective effects due to its saikosaponin content; monitoring is warranted in animals on hepatically metabolized medications or those with pre-existing hepatic conditions, where saikosaponin's effects on hepatic enzyme activity could interact with medication metabolism.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eQi stagnation resolving and liver qi moving through Xiang Fu (19%):\u003c\/strong\u003e Moves the liver qi, resolves qi stagnation, harmonizes the middle jiao, and addresses the emotional and digestive manifestations of liver qi constraint through Xiang Fu (cyperus rhizome, Rhizoma Cyperi Rotundi). Xiang Fu's acrid, slightly bitter, and neutral nature enters the liver, triple burner, and spleen channels to move the liver qi broadly through all three burners, making it particularly effective for the full-body manifestations of liver qi stagnation that affect the emotional state, the digestive system, and the rib-side region simultaneously. Xiang Fu is one of the most important single herbs in classical materia medica for liver qi stagnation across all its manifestations. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eQi stagnation breaking and chest and rib-side opening through Zhi Ke (19%):\u003c\/strong\u003e Breaks qi stagnation, descends the qi, and opens the chest and rib-side region to relieve the tension and stagnation that liver qi stagnation generates in the chest and flank through Zhi Ke (bitter orange fruit, Fructus Citri Aurantii). Zhi Ke's bitter, acrid, and slightly cold nature enters the spleen, stomach, and large intestine channels to move and descend the stagnant qi in the middle and upper burner, addressing the rib-side tension and chest oppression that are the formula's key local manifestations of liver qi stagnation. Zhi Ke's qi-moving action complements Chai Hu and Xiang Fu's liver-coursing action by ensuring the stagnant qi is moved downward and outward as well as released from the liver channel. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eBlood activation and liver blood nourishment through Chuan Xiong (12%):\u003c\/strong\u003e Activates the blood, moves the qi, dispels wind, and addresses the blood stagnation that prolonged liver qi stagnation generates in the channels through Chuan Xiong (ligusticum rhizome, Radix Ligustici Chuanxiong). Chuan Xiong's acrid and warm nature enters the liver, gallbladder, and pericardium channels to activate the blood and move the qi simultaneously, addressing both the secondary blood stagnation that liver qi stagnation generates over time and the qi stagnation directly through the blood-qi relationship. In the formula's architecture, Chuan Xiong ensures the formula addresses both the blood and qi levels of the stagnation, preventing purely qi-moving herbs from generating heat without addressing the blood component. Antiplatelet effects from ligustilide and ferulic acid content; monitoring warranted in animals on anticoagulant medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eLiver blood nourishment and liver yin support through Bai Shao (19%):\u003c\/strong\u003e Nourishes the liver blood, softens the liver, harmonizes the liver and spleen, and moderates the formula's dispersing herbs through Bai Shao (white peony root, Radix Paeoniae Lactiflorae). Bai Shao's bitter, sour, and slightly cold nature enters the liver and spleen channels to nourish the liver blood and yin that the stagnation pattern is depleting, and to soften the liver's tendency toward constraint by nourishing the substance (blood and yin) that the liver wood requires to maintain its free coursing function. Bai Shao's presence at 19% reflects the classical principle that liver qi stagnation is always accompanied by some degree of liver blood and yin insufficiency - the constraint depletes the substance, and the substance insufficiency worsens the constraint. Generally well tolerated; mild antiplatelet effects from paeoniflorin content.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eQi moving and middle jiao harmonizing through Chen Pi:\u003c\/strong\u003e Moves the qi, dries dampness, harmonizes the middle jiao, and addresses the digestive irregularities that liver qi stagnation and liver-spleen disharmony generate through Chen Pi (tangerine peel, Pericarpium Citri Reticulatae). Chen Pi's acrid, bitter, and warm nature enters the spleen, stomach, and lung channels to move qi in the middle jiao and dry the dampness generated by liver-spleen disharmony, addressing the bloating, borborygmus, and digestive irregularity component of the liver qi stagnation pattern. Chen Pi complements the formula's liver-coursing herbs by ensuring the middle jiao qi is also moved, and the spleen's transforming function is supported alongside the liver's coursing function. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFormula harmonization and liver-spleen harmonizing through Zhi Gan Cao (6%):\u003c\/strong\u003e Harmonizes the formula's herbs, moderates the dispersing nature of the qi-moving herbs, tonifies the qi and spleen, and harmonizes the liver and spleen relationship through Zhi Gan Cao (honey-fried licorice root, Honey-fried Radix Glycyrrhizae Uralensis). The honey-fried preparation strengthens Gan Cao's qi-tonifying and spleen-harmonizing properties, making it particularly appropriate in a formula addressing liver-spleen disharmony where the spleen's qi requires support alongside the liver's qi-moving treatment. Glycyrrhizin content with mineralocorticoid-like effects; monitoring warranted with corticosteroids and antihypertensive medications in long-term use.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eTCVM Principles\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003ePrimary action - liver qi stagnation with liver-spleen disharmony through the combined strategy of spreading the liver qi and releasing constraint (Chai Hu, Xiang Fu, Zhi Ke, Chen Pi), activating the blood and nourishing the liver (Chuan Xiong, Bai Shao), and harmonizing the liver and spleen while moderating the formula's moving herbs (Zhi Gan Cao):\u003c\/strong\u003e Addresses the liver qi stagnation pattern through three simultaneous therapeutic strategies. Chai Hu courses the liver qi and releases the constrained liver wood directly; Xiang Fu moves the liver qi through all three burners; Zhi Ke opens the chest and rib-side and descends the stagnant qi; Chen Pi moves the middle jiao qi and harmonizes the spleen. Chuan Xiong activates the blood and addresses the secondary blood stagnation; Bai Shao nourishes the liver blood and yin to address the substance component of the constraint. Zhi Gan Cao harmonizes the liver and spleen and moderates the formula's dispersing action. Treatment Principles: spread the liver qi, harmonize the liver and spleen, activate the blood, and address rib-side tension and stagnation-related discomfort.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eSecondary action - pattern differentiation from liver fire (requiring stronger heat-clearing herbs), liver blood vacuity without qi stagnation (requiring blood-nourishing formulas without the strong qi-moving emphasis), and liver yang rising (requiring descending and anchoring herbs):\u003c\/strong\u003e Chai Hu Shu Gan San is indicated specifically for the liver qi stagnation pattern with liver-spleen disharmony, not for liver fire (which requires cold-clearing herbs and less acrid dispersing action), liver blood vacuity without significant qi stagnation (where the formula's strong qi-moving herbs could further deplete the blood), or liver yang rising (which requires descending and anchoring strategies). Clinical differentiation centers on the wiry pulse, behavioral and emotional signs of constraint (irritability, restlessness, tension), rib-side and flank sensitivity, and digestive signs of liver-spleen disharmony without significant heat signs. Your authorizing veterinarian will confirm the liver qi stagnation pattern through tongue and pulse examination, along with behavioral and clinical assessment.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eAvailable Forms\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003ePowder - Canine Blend (for dogs and cats):\u003c\/strong\u003e Available in 75 g, 150 g, 500 g, 900 g, and 1200 g sizes; mix into food at the recommended dose for your pet's weight. Cats and dogs both use this blend.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003ePowder - Equine\/Horse Blend (for horses):\u003c\/strong\u003e Available in 150 g, 500 g, 900 g, and 1200 g sizes; mix into grain at the recommended dose for your horse.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eSuggested Use\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFor Dogs (Canine Blend Powder):\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eUnder 30 lbs: ½ tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e30-80 lbs: 1 tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e80-120 lbs: 1½ tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eOver 120 lbs: 2 tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFor Cats (Canine Blend Powder):\u003c\/strong\u003e ¼ tsp twice daily, or as prescribed\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eFor Horses (Equine\/Horse Blend, 1,000 lb horse):\u003c\/strong\u003e Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase. Most horses will readily accept the herbs in their grain.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eIngredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eActive Ingredients:\u003c\/strong\u003e Chai Hu (Radix Bupleuri) (25%), Bai Shao (Radix Paeoniae Lactiflorae) (19%), Xiang Fu (Rhizoma Cyperi Rotundi) (19%), Zhi Ke (Fructus Citri Aurantii) (19%), Chuan Xiong (Radix Ligustici Chuanxiong) (12%), Zhi Gan Cao (Honey-fried Radix Glycyrrhizae Uralensis) (6%), Chen Pi (Pericarpium Citri Reticulatae)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eInactive Ingredient:\u003c\/strong\u003e Flaxseed\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eVETERINARY AUTHORIZATION REQUIRED: \u003ca href=\"https:\/\/tcvmpet.com\/pages\/get-an-authorization\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eSubmit Your Authorization Request\u003c\/a\u003e or \u003ca href=\"https:\/\/tcvmpet.com\/pages\/schedule-a-consultation\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eRequest a TCVM Telemedicine Consultation\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eActive Ingredient TCVM Actions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eChai Hu Shu Gan San is a seven-herb formula organized around three therapeutic strategies: liver qi spreading and constraint releasing (Chai Hu, Xiang Fu, Zhi Ke, Chen Pi), blood activation and liver nourishment (Chuan Xiong, Bai Shao), and liver-spleen harmonization (Zhi Gan Cao): \u003c\/span\u003e\u003c\/p\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eChai Hu (Radix Bupleuri) - Bupleurum Root:\u003c\/strong\u003e Chief herb; spreads the liver qi and releases liver qi constraint directly. Saikosaponin content with hepatic enzyme activity effects; monitoring warranted with hepatically metabolized medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eBai Shao (Radix Paeoniae Lactiflorae) - White Peony Root:\u003c\/strong\u003e Nourishes the liver blood and yin, softens the liver, and harmonizes the liver and spleen; addresses the blood and yin insufficiency component of the constraint pattern. Mild antiplatelet effects from paeoniflorin.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eXiang Fu (Rhizoma Cyperi Rotundi) - Cyperus Rhizome:\u003c\/strong\u003e Moves the liver qi through all three burners; addresses the full-body manifestations of liver qi stagnation. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eZhi Ke (Fructus Citri Aurantii) - Bitter Orange Fruit:\u003c\/strong\u003e Breaks qi stagnation, descends the qi, and opens the chest and rib-side; addresses the local manifestations of liver qi stagnation in the thorax and flank. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eChuan Xiong (Radix Ligustici Chuanxiong) - Ligusticum Root \/ Szechuan Lovage Root:\u003c\/strong\u003e Activates the blood and moves the qi; addresses the secondary blood stagnation that liver qi stagnation generates. Antiplatelet effects from ligustilide and ferulic acid; monitoring warranted with anticoagulant medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eZhi Gan Cao (Honey-fried Radix Glycyrrhizae Uralensis) - Honey-Fried Licorice Root:\u003c\/strong\u003e Harmonizes the formula, tonifies the qi and spleen, and moderates the dispersing herbs; strengthened spleen-tonifying action from honey-frying. Glycyrrhizin content; monitoring warranted with corticosteroids and antihypertensive medications.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eChen Pi (Pericarpium Citri Reticulatae) - Tangerine Peel \/ Aged Citrus Peel:\u003c\/strong\u003e Moves the middle jiao qi and dries dampness; addresses the digestive and spleen component of liver-spleen disharmony. Generally well tolerated.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003ePotential Drug Interactions\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eChai Hu Shu Gan San has a moderate drug interaction profile. The primary concern is Chai Hu's saikosaponin content, which affects hepatic cytochrome P450 enzyme activity and can alter the metabolism of medications processed by these pathways, warranting veterinary review of all hepatically metabolized medications before use. Secondary concerns include Chuan Xiong's ligustilide and ferulic acid antiplatelet effects (monitoring warranted in animals on anticoagulant or antiplatelet medications, where the combined blood-activating effect of Chuan Xiong and Bai Shao could compound the medication's effects); Zhi Gan Cao's glycyrrhizin-based mineralocorticoid-like effects (monitoring warranted with corticosteroids, where additive effects on fluid retention and electrolytes are possible, and antihypertensive medications, where the fluid-retaining tendency could counteract the medication); and Bai Shao's paeoniflorin antiplatelet effects (mild, but additive with Chuan Xiong in animals on anticoagulant medications).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eMedication categories warranting extra caution: hepatically metabolized medications subject to CYP enzyme interactions (Chai Hu saikosaponin effects - primary concern), anticoagulant and antiplatelet medications (Chuan Xiong and Bai Shao combined antiplatelet effects), corticosteroids (Zhi Gan Cao glycyrrhizin additive mineralocorticoid effects), and antihypertensive medications (Zhi Gan Cao fluid-retaining tendency). Your authorizing veterinarian will determine appropriateness based on your animal's condition, current medications, and confirmation of the liver qi stagnation pattern through tongue quality, pulse character, and behavioral and clinical assessment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cstrong\u003eVETERINARY AUTHORIZATION REQUIRED: \u003ca href=\"https:\/\/tcvmpet.com\/pages\/get-an-authorization\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eSubmit Your Authorization Request\u003c\/a\u003e or \u003ca href=\"https:\/\/tcvmpet.com\/pages\/schedule-a-consultation\" rel=\"noopener\" style=\"color: rgb(0, 0, 0);\" target=\"_blank\"\u003eRequest a TCVM Telemedicine Consultation\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eFrequently Asked Questions\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eWhat conditions is Chai Hu Shu Gan San used for in TCVM?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eIn Traditional Chinese Veterinary Medicine, Chai Hu Shu Gan San is indicated for the liver qi stagnation pattern with liver-spleen disharmony. The clinical presentation centers on irritability, emotional tension, or behavioral changes reflecting constrained liver wood energy; rib-side or flank sensitivity; digestive irregularities including bloating, borborygmus, or alternating loose and firm stools from liver-spleen disharmony; and a wiry pulse reflecting constrained liver qi. The formula is particularly well suited for animals whose liver qi stagnation has a clear behavioral or emotional component alongside the physical signs, and for cases where rib-side tension and digestive irregularity coexist as the primary presentation. Your authorizing veterinarian will confirm the liver qi stagnation pattern through tongue and pulse examination, along with behavioral and clinical assessment.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eHow is Chai Hu Shu Gan San administered to dogs, cats, and horses?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eMix the powder into food or grain at the dose recommended for your animal's species and body weight. Dogs and cats use the Canine Blend; horses use the Equine\/Horse Blend. All species receive the formula twice daily, with horses following the standard 20-day twice-daily loading protocol before transitioning to once-daily maintenance dosing. Because Chai Hu Shu Gan San contains Chai Hu with potential hepatic enzyme interactions, veterinary review of all current medications is important before use. The formula's qi-moving and blood-activating herbs make veterinary monitoring appropriate in animals on anticoagulant medications.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eHow long does it take to see results with Chai Hu Shu Gan San?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eBecause it addresses qi stagnation rather than deep constitutional vacuity, Chai Hu Shu Gan San typically shows relatively early improvement in the most responsive signs. Early improvement in behavioral signs of liver qi constraint (reduced irritability, decreased tension, improved emotional ease) and rib-side sensitivity may appear within 1 to 3 weeks as the formula's liver-coursing and qi-moving herbs begin addressing the stagnation. Improvement in the wiry pulse quality and digestive normalization typically requires 3 to 6 weeks. Chronic liver qi stagnation with established liver-spleen disharmony may require 2 to 3 months of treatment before the pattern is meaningfully resolved. Your authorizing veterinarian will monitor pulse quality, behavioral signs, and digestive function throughout the treatment course.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eCan Chai Hu Shu Gan San be combined with other herbal formulas?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003eChai Hu Shu Gan San is sometimes used alongside other formulas when the liver qi stagnation pattern coexists with additional patterns requiring treatment, but all formula combinations require veterinary authorization and supervision. Common clinical scenarios where combination is considered include liver qi stagnation with underlying liver blood vacuity (where a blood-nourishing formula may be added), liver qi stagnation with heat signs that the formula's mild cold-natured herbs cannot address alone, or liver-spleen disharmony with significant spleen qi vacuity requiring additional spleen support. Because the formula's qi-moving and blood-activating herbs can interact with each other and with other formulas' blood-moving herbs, a comprehensive veterinary review of all formulas and medications used together is required before initiating any combination.\u003c\/span\u003e\u003c\/p\u003e"}