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Herbsmith Rx Xiao Yao San is a classical Chinese herbal formula recommended by holistic veterinarians to support liver qi flow, spleen function, and blood nourishment in dogs, cats, and horses. Based on the traditional formula Xiao Yao San (also known as Tang Kuei and Bupleurum Combination, Rambling Powder, Free and Easy Wanderer, Liver Happy, Relaxed Wanderer, Bupleurum and Tang Kuei, and Rambling Ease Powder), it spreads the liver qi, strengthens the spleen, and nourishes the blood. One of the most widely used formulas in Traditional Chinese Medicine, it is well suited for pets presenting with liver qi stagnation causing digestive irregularity, bloating, irritability, restlessness, or anxiety, particularly where blood deficiency underlies or accompanies the stagnation. Available as a concentrated powder mixed into food; cats and dogs use the Canine Blend, while horses use the Equine/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.
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For Dogs (Canine Blend Powder):
For Cats (Canine Blend Powder): ¼ tsp twice daily, or as prescribed
For Horses (Equine/Horse Blend, 1,000 lb horse): Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase until the horse is accustomed to the taste. Most horses will readily accept the herbs in their grain.
Active Ingredients: Chai Hu (Radix Bupleuri), Dang Gui (Radix Angelicae Sinensis), Bai Shao (Radix Paeoniae Lactiflorae), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Fu Ling (Sclerotium Poriae Cocos), Zhi Gan Cao (Honey-fried Radix Glycyrrhizae Uralensis)
Inactive Ingredient: Flaxseed
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Xiao Yao San is a six-herb formula that balances liver, spleen, and blood in one of the most elegant and widely used combinations in Traditional Chinese Medicine, addressing both the root and branch of liver qi stagnation with blood deficiency:
Xiao Yao San contains liver-regulating and blood-nourishing herbs including Chai Hu and Dang Gui, which have mild hormone-influencing and hepatic-metabolizing properties. Pets currently on prescription medications should use this formula under veterinary supervision, as herb-drug interaction research in dogs and cats remains limited.
Medication categories warranting extra caution include hepatic medications or drugs with significant liver metabolism, hormonal therapies, immunosuppressive drugs, and pets managing multiple concurrent prescriptions. Your authorizing veterinarian can determine appropriateness based on your pet's condition, current medications, and laboratory results.
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In Traditional Chinese Veterinary Medicine, Xiao Yao San is indicated for liver qi stagnation with underlying blood deficiency, presenting as digestive irregularity, bloating, irritability, restlessness, anxiety, and a wiry or thin pulse. It is one of the most widely used formulas in TCVM and is a good alternative to Tang Kuei and Bupleurum Combination, Rambling Powder, Free and Easy Wanderer, Liver Happy, Relaxed Wanderer, Bupleurum and Tang Kuei, and Rambling Ease Powder. It is appropriate for pets whose behavioral or digestive signs have a liver qi and blood deficiency component.
Mix the powder directly into food or grain at the dose recommended for your pet's species and body weight. Both dogs and cats use the Canine Blend; horses use the Equine/Horse Blend. Dogs and cats receive the formula twice daily; horses receive two tablespoons twice daily for the first 20 days, then once daily for maintenance. Your authorizing veterinarian will confirm the appropriate dose and schedule for your individual pet.
Response time varies depending on the severity and chronicity of the liver qi stagnation and blood deficiency pattern. Many pets show improvement in digestive regularity, bloating, restlessness, and behavioral balance within 3 to 6 weeks of consistent use. Chronic or deeply rooted patterns may require a longer course of treatment, and your veterinarian may recommend periodic reassessment to adjust the formula or dosing as your pet responds.
Combination with complementary TCVM formulas is common in holistic veterinary practice and should be guided by your authorizing veterinarian based on your pet's full pattern diagnosis. Because this formula contains Chai Hu, which is processed by the liver and may influence hormonal regulation, veterinary oversight is especially important if your pet is on hepatic medications, hormonal therapies, or immunosuppressive drugs, to ensure the treatment plan is appropriate for your pet's overall health status.
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