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Herbsmith Rx Si Wu San is the classical foundational Chinese herbal formula for blood tonification, recommended by holistic veterinarians to tonify the blood and regulate the liver in dogs, cats, and horses. Comparable to Four Substance Powder, Si Wu Tang, Dandruff Formula, and Four Materials Combination, it tonifies the blood and regulates the liver, addressing Chong and Ren vacuity and blood vacuity. Well suited for pets and horses presenting with liver blood deficiency and Chong and Ren vessel insufficiency, with signs such as pale or dry mucous membranes, lusterless coat, fatigue, weakness, hind limb weakness or atrophy, dry skin, reproductive irregularities, and the general signs of blood deficiency failing to nourish the liver, uterus, Chong and Ren vessels, sinews, and superficial tissues. Available as a concentrated powder mixed into food; cats and dogs use the Canine Blend, while horses use the Equine/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.
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For Dogs (Canine Blend Powder):
For Cats (Canine Blend Powder): ¼ tsp twice daily, or as prescribed
For Horses (Equine/Horse Blend, 1,000 lb horse): Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase until the horse is accustomed to the taste. Most horses will readily accept the herbs in their grain.
Active Ingredients: Shu Di Huang (Radix Rehmanniae Glutinosae Conquitae), Bai Shao (Radix Paeoniae Lactiflorae), Dang Gui (Radix Angelicae Sinensis), Chuan Xiong (Radix Ligustici Chuanxiong)
Inactive Ingredient: Flaxseed
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Si Wu San is the classical four-herb blood tonification formula of Chinese medicine, combining a principal blood tonic, a blood-nourishing and blood-moving dual-action herb, a liver blood nourisher and liver softener, and a blood invigorator and qi mover to tonify the blood and regulate the liver from four complementary angles:
Si Wu San contains blood-nourishing and blood-moving herbs including Dang Gui, Chuan Xiong, and Bai Shao, which have mild effects on platelet aggregation, blood viscosity, and smooth muscle tone. Pets currently on anticoagulant, antiplatelet, or hormone-based medications should use this formula under veterinary supervision, as Dang Gui and Chuan Xiong have known mild blood-thinning and blood-moving actions that may have additive effects with pharmaceutical blood thinners, and herb-drug interaction research in dogs, cats, and horses remains limited.
Medication categories warranting extra caution include anticoagulant or antiplatelet medications, non-steroidal anti-inflammatory drugs, hormone therapies or reproductive medications, and cardiac medications. Your authorizing veterinarian can determine appropriateness based on your animal's condition, current medications, and laboratory results.
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In Traditional Chinese Veterinary Medicine, Si Wu San is the foundational formula for liver blood vacuity and Chong and Ren vessel insufficiency, presenting with pale or dry mucous membranes, lusterless coat, fatigue, weakness, hind limb weakness or atrophy, dry skin, and reproductive irregularities arising from insufficient blood failing to nourish the liver, sinews, uterus, and Chong and Ren vessels. Comparable to Four Substance Powder, Si Wu Tang, Dandruff Formula, and Four Materials Combination, it is the classical base formula from which many blood-nourishing TCVM formulas are derived, including Tao Hong Si Wu San and Si Wu Xiao Feng San, and is appropriate when a straightforward blood tonification and liver regulation approach is indicated without the need for additional wind-expelling, stasis-resolving, or heat-clearing herbs.
Mix the powder directly into food or grain at the dose recommended for your animal's species and body weight. Dogs and cats use the Canine Blend; horses use the Equine/Horse Blend. Dogs and cats receive the formula twice daily; horses receive two tablespoons twice daily for the first 20 days, then once daily for maintenance. If the horse initially refuses, start with a small amount mixed into grain and gradually increase until the horse is accustomed to the taste. Most horses will readily accept the herbs in their grain. Your authorizing veterinarian will confirm the appropriate dose and schedule for your individual animal.
Many pets show improvement in coat quality, energy, and general vitality within 4 to 6 weeks of consistent use as the blood is tonified and the liver blood is restored. Because liver blood deficiency and Chong and Ren insufficiency are chronic deficiency patterns, a longer course of treatment of 8 to 12 weeks or more is typically needed to adequately nourish the blood and maintain the improvement in the signs of blood deficiency. Your veterinarian may recommend periodic reassessment to evaluate the pattern's response and adjust the treatment plan as the liver blood is gradually restored.
Si Wu San is the foundational four-herb blood tonification formula from which many related TCVM formulas are derived. Tao Hong Si Wu San adds Tao Ren and Hong Hua to address concurrent blood stasis alongside blood deficiency. Si Wu Xiao Feng San adds wind-expelling and heat-clearing herbs to address blood deficiency wind patterns in the skin. Ba Zhen San adds the four qi-tonifying herbs of Si Jun Zi Tang to address concurrent qi and blood deficiency. Your authorizing veterinarian will determine which blood-nourishing formula best matches your animal's full TCVM pattern diagnosis based on the presenting signs and the specific pattern of deficiency involved.
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