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Herbsmith Rx Dang Gui Shao Yao San is a classical Chinese herbal formula recommended by holistic veterinarians to nourish the liver blood, spread the liver qi, strengthen the spleen, and resolve dampness in dogs, cats, and horses. Also known as Tangkuei and Peony Powder and Angelica and Peony Combination, Dang Gui Shao Yao San is a six-herb formula that addresses the combined pattern of liver blood vacuity with spleen qi weakness and dampness accumulation - a pattern in which the liver's insufficient blood compromises its free-flowing function and generates secondary liver qi constraint, while the spleen's weakened qi fails to transform and transport fluids and allows pathological dampness to accumulate in the middle and lower jiao. The formula's six herbs address this combined pattern from three simultaneous directions: nourishing and activating the liver blood (Dang Gui, Shao Yao, Chuan Xiong) so the liver has the blood substrate needed to maintain its free-flowing function; strengthening the spleen qi and drying the dampness that the spleen's compromised transforming function has allowed to accumulate (Bai Zhu, Fu Ling); and draining the accumulated pathological dampness from the lower jiao through the urinary pathway (Ze Xie, Fu Ling). Well suited for dogs, cats, and horses presenting with the combined liver blood vacuity and spleen dampness pattern, characterized by a pale or pale-lavender tongue with a greasy or slippery coating reflecting both the blood vacuity (pale) and the dampness accumulation (greasy, slippery); a fine and wiry or fine and slippery pulse reflecting the blood vacuity (fine) and the liver constraint or dampness (wiry, slippery); chronic fatigue and general debility from blood vacuity failing to nourish the body; abdominal fullness, bloating, or digestive irregularity from spleen qi weakness and dampness obstructing the middle jiao; mild musculoskeletal stiffness or cramping from liver blood vacuity failing to nourish the sinews; and urinary irregularity or fluid accumulation in the lower jiao from dampness failing to be transformed and drained. Available as a concentrated powder mixed into food; dogs and cats use the Canine Blend, while horses use the Equine/Horse Blend. Dosing varies by species and body weight, and your authorizing veterinarian will provide specific guidance.
VETERINARY AUTHORIZATION REQUIRED: Submit Your Authorization Request or Request a TCVM Telemedicine Consultation
For Dogs (Canine Blend Powder):
For Cats (Canine Blend Powder): ¼ tsp twice daily, or as prescribed
For Horses (Equine/Horse Blend, 1,000 lb horse): Two tablespoons twice daily for 20 days, then two tablespoons once daily in grain. If the horse initially refuses, start with a small amount mixed into grain and gradually increase until the horse is accustomed to the taste. Most horses will readily accept the herbs in their grain.
Active Ingredients: Dang Gui (Radix Angelicae Sinensis), Shao Yao (Radix Paeoniae), Fu Ling (Sclerotium Poriae Cocos), Bai Zhu (Rhizoma Atractylodis Macrocephalae), Ze Xie (Rhizoma Alismatis Orientalis), Chuan Xiong (Radix Ligustici Chuanxiong)
Inactive Ingredient: Flaxseed
VETERINARY AUTHORIZATION REQUIRED: Submit Your Authorization Request or Request a TCVM Telemedicine Consultation
Dang Gui Shao Yao San is a six-herb formula organized around three paired therapeutic strategies: Dang Gui, Shao Yao, and Chuan Xiong for liver blood nourishment and activation; Bai Zhu and Fu Ling for spleen qi strengthening and dampness drying; and Ze Xie and Fu Ling for lower jiao dampness draining:
Dang Gui Shao Yao San's primary drug interaction concern is the compounded anticoagulant and antiplatelet effect of its three blood-activating herbs: Dang Gui's coumarin-based anticoagulant effects, Chuan Xiong's ligustilide and ferulic acid antiplatelet effects, and Shao Yao's paeoniflorin antiplatelet effects combine to create a meaningful anticoagulant interaction risk in animals on warfarin, heparin, aspirin, clopidogrel, and other anticoagulant or antiplatelet medications. This combined blood-activating interaction is the formula's primary drug interaction category and requires veterinary coordination before use in animals on any anticoagulant treatment. Bai Zhu has mild anticoagulant effects that add to this combined concern. Ze Xie's cold and draining nature and its effects on fluid metabolism warrant caution in animals on diuretic medications where the combined fluid-draining action could compound the medication's effect. The formula's cold and dampness-draining strategy (Ze Xie, Fu Ling) is not appropriate for animals with significant kidney yang vacuity, yang vacuity cold patterns, or significant constitutional cold where the draining herbs would further deplete the yang.
Medication categories warranting extra caution include anticoagulant and antiplatelet medications (compounded effects of Dang Gui, Chuan Xiong, Shao Yao, and Bai Zhu), diuretic medications (Ze Xie and Fu Ling combined fluid-draining action), and medications metabolized by the liver's CYP enzyme system where Chuan Xiong's interaction potential warrants review. Your authorizing veterinarian will determine appropriateness based on your animal's condition, current medications, and confirmation of the combined liver blood vacuity and spleen dampness pattern through tongue quality (pale with greasy or slippery coating), pulse character (fine with wiry or slippery quality), and clinical assessment of the nourishment-failure and dampness accumulation signs.
VETERINARY AUTHORIZATION REQUIRED: Submit Your Authorization Request or Request a TCVM Telemedicine Consultation
In Traditional Chinese Veterinary Medicine, Dang Gui Shao Yao San is indicated for the combined liver blood vacuity and spleen dampness pattern, where insufficient liver blood compromises the liver's free-flowing function and generates secondary qi constraint, while spleen qi weakness fails to transform and transport fluids, allowing pathological dampness to accumulate. The clinical presentation centers on a pale or pale-lavender tongue with a greasy or slippery coating reflecting both the blood vacuity and dampness accumulation; a fine and wiry or fine and slippery pulse; chronic fatigue and general debility from blood vacuity; abdominal fullness, bloating, or digestive irregularity from middle jiao dampness; mild musculoskeletal stiffness or cramping from liver blood failing to nourish the sinews; and fluid accumulation or urinary irregularity from lower jiao dampness. Your authorizing veterinarian will confirm the combined pattern through tongue and pulse examination and clinical assessment.
Mix the powder directly into food or grain at the dose recommended for your animal's species and body weight. Dogs and cats use the Canine Blend; horses use the Equine/Horse Blend. All species receive the formula twice daily, with horses following the standard 20-day twice-daily loading protocol before transitioning to once-daily maintenance dosing. Because Dang Gui Shao Yao San contains three herbs with anticoagulant and antiplatelet effects (Dang Gui, Chuan Xiong, Shao Yao), comprehensive veterinary review of current medications is required before use, particularly for animals on anticoagulant or antiplatelet treatments. The formula's dampness-draining strategy (Ze Xie, Fu Ling) is not appropriate for animals with significant kidney yang vacuity or yang vacuity cold patterns.
As a formula addressing a combined constitutional blood vacuity and dampness accumulation pattern, Dang Gui Shao Yao San typically shows improvement in two stages: early improvement in the dampness accumulation signs (reduced abdominal fullness, improved digestive comfort, improved urinary function) may be seen within 2 to 4 weeks as the formula's dampness-draining herbs (Ze Xie, Fu Ling) begin clearing the accumulated dampness. More substantial restoration of the liver blood, reflected in improved energy, reduced sinew stiffness, and normalization of the tongue color from pale toward pink with resolution of the greasy coating, typically requires 4 to 8 weeks or longer. Deeply established liver blood vacuity with chronic dampness accumulation may require 3 to 6 months of sustained treatment before the pattern is meaningfully resolved. Your authorizing veterinarian will monitor tongue, pulse, and clinical signs throughout the treatment course.
Dang Gui Shao Yao San differs from Bu Gan San and other pure liver blood-nourishing formulas in its significant spleen-strengthening and dampness-draining component: where Bu Gan San (built on the Si Wu Tang core with Suan Zao Ren and Mu Gua) focuses primarily on liver blood and yin nourishment with spirit calming and sinew relaxation as secondary actions, Dang Gui Shao Yao San devotes three of its six herbs (Bai Zhu, Fu Ling, Ze Xie) to the spleen-strengthening and dampness-resolving side of the pattern. This makes Dang Gui Shao Yao San the formula of choice when the combined liver blood vacuity and spleen dampness pattern is present together - when the tongue shows both the pale color of blood vacuity and the greasy or slippery coating of dampness, and when the clinical signs include both the nourishment-failure signs of blood vacuity and the accumulation signs of dampness. Bu Gan San is more appropriate when liver blood and yin vacuity with spirit disturbance and sinew malnourishment predominates without significant dampness accumulation. Your authorizing veterinarian will determine which formula best matches your animal's specific pattern.
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