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Herbsmith Microflora Plus goes beyond probiotics alone. This 4-in-1 synbiotic formula combines probiotics, prebiotics, digestive enzymes, and gut-soothing herbs to restore balance to your pet's microbiome - the ecosystem that supports digestion, immunity, and everyday vitality. Formulated by Dr. Chris Bessent, a holistic veterinarian with 30+ years of experience, Microflora Plus delivers comprehensive gut support for dogs and cats in a single easy-to-administer capsule that can be given whole or opened and mixed into food.
Loose stool, gas, or upset tummies can signal that your pet's microbiome is out of balance. The gut is home to trillions of bacteria that influence everything from nutrient absorption to overall well-being. Supporting these good bacteria keeps pets thriving from nose to tail. Add Microflora Plus to their bowl each day to help maintain lasting gut balance and everyday digestive health.
Every pet deserves a thriving microbiome. Where other products focus on one function, Microflora Plus supports the entire digestive ecosystem through true 4-in-1 synbiotic support:
Give capsules directly or open and mix the contents with food. Dose by body weight daily:
This product is intended for intermittent or supplemental feeding only. Safe use in pregnant animals or animals intended for breeding has not been established. If your pet's condition worsens or does not improve, discontinue use and consult your veterinarian.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Active ingredients (per two capsules): Bacillus and Lactobacillus blend (dried fermentation products of Bacillus subtilis and Bacillus licheniformis, dried Lactobacillus acidophilus fermentation product) 10 billion CFU; FOS (Fructooligosaccharides) 100 mg; Digestive enzyme blend (dried fermentation products of Aspergillus oryzae, Rhizopus oryzae, and Trichoderma longibrachiatum, pineapple stem, papaya) including amylase 3,750 SKB/g, protease 5,625 HUT/g, lipase 750 FIP/g, cellulase 600 CU/g, bromelain 22.5 GDU/g, papain 3.75 TU/mg; Cinnamon Bark, Ginger, Licorice 270 mg.
Inactive ingredients: Maltodextrin, stearic acid, sodium silico aluminate (desiccant).
Bacillus and Lactobacillus Blend: These spore-forming and lactic acid-producing probiotic strains are among the most researched beneficial bacteria for gastrointestinal health. Bacillus subtilis and Bacillus licheniformis are heat-stable spore formers that survive the digestive tract effectively, supporting lasting colonization of the gut microbiome. Lactobacillus acidophilus helps maintain a favorable intestinal environment and supports the gut lining. Soil-based Bacillus strains are particularly valued for their stability and ability to survive the harsh conditions of the upper digestive tract to reach the lower intestine, where they exert their benefits.
FOS (Fructooligosaccharides): A prebiotic fiber that selectively feeds beneficial bacteria in the large intestine, helping established probiotic populations thrive. FOS is not digested by the host animal and passes intact to the colon where it ferments and supports microbial balance, creating the nutritional environment the probiotic strains need to colonize and persist.
Digestive Enzyme Blend: Amylase breaks down starches; protease breaks down proteins; lipase breaks down fats; cellulase breaks down plant cellulose; bromelain (from pineapple stem) and papain (from papaya) are plant-derived proteolytic enzymes traditionally used to support protein digestion and digestive comfort. Together, these six enzymes support thorough macronutrient breakdown and efficient absorption across protein, fat, carbohydrate, and plant fiber fractions of the diet.
Cinnamon Bark (Cinnamomum spp.): Traditionally used in herbal practice to support digestive warmth and comfort. In TCVM, cinnamon is considered warming in nature and is used to support Yang and move Qi through the digestive tract, making it appropriate for digestive presentations with Cold or Qi stagnation components.
Ginger (Zingiber officinale): A well-documented digestive botanical traditionally used to support stomach comfort and gastrointestinal motility. Ginger is warming in nature and is used in both Western herbal practice and TCVM to support digestive function, ease occasional GI discomfort, and resolve Dampness in the Middle Jiao.
Licorice (Glycyrrhiza glabra): Traditionally used to soothe and support the gastrointestinal mucosa. In TCVM, licorice is the classical harmonizing herb that moderates the actions of other herbs in a formula and supports the Spleen and Stomach; its inclusion in the herbal blend ensures the warming herbs are balanced, and the overall formula action is gentle and sustained rather than acute.
Microflora Plus contains digestive herbs including cinnamon, ginger, and licorice that may interact with certain medications, particularly those affecting blood glucose, blood pressure, or corticosteroid metabolism. Licorice's glycyrrhizin constituent warrants caution in pets on corticosteroids or antihypertensive medications. Pets on prescription medications should use this supplement under veterinary supervision, as herb-drug interaction research in dogs and cats remains limited.
Pets with chronic health conditions or those on ongoing prescription medications may benefit from periodic bloodwork monitoring as recommended by their veterinarian. Your veterinarian can evaluate whether this supplement is appropriate based on your pet's condition, current medications, and laboratory results.
Herbsmith was founded by Dr. Chris Bessent, holistic veterinarian with 30+ years of experience in traditional Chinese veterinary medicine and Western veterinary practice. Herbsmith formulas are developed with a dual focus: honoring the classical traditions of TCVM while meeting modern standards for quality, safety, and efficacy. Each formula is manufactured in an FDA-registered, cGMP-compliant facility in the United States and undergoes rigorous third-party testing. Herbsmith carries the National Animal Supplement Council (NASC) Quality Seal, awarded only to companies that meet and exceed the NASC's rigorous standards for quality, safety, and adverse event reporting. Herbsmith is committed to providing veterinarians and pet owners with integrative solutions that support the whole animal.
Microflora Plus supports digestive health, healthy gut flora, immune resilience, and bowel comfort in both dogs and cats. Its 4-in-1 synbiotic formula addresses the full digestive ecosystem: probiotics to populate and balance the microbiome, prebiotics to feed and sustain the probiotic colonies, digestive enzymes to support efficient nutrient absorption, and soothing herbs to support gut lining comfort and bowel regularity. It is particularly useful during periods of dietary transition, environmental stress, or whenever a pet needs additional daily support for stool consistency, digestion, and immune function. This product is not intended to diagnose or treat any disease and is best used as part of a regular daily wellness routine.
Capsules can be given whole or opened and the contents mixed into food. For dogs, dosing is based on body weight: 1/2 capsule per day for dogs under 20 lbs, 1 capsule per day for dogs 21-40 lbs, 2 capsules per day for dogs 41-80 lbs, and 3 capsules per day for dogs over 81 lbs. Cats receive 1/2 capsule per day. Consult your veterinarian if you have questions about the appropriate dose for your pet's specific situation.
Many pet owners report noticing improvements in stool consistency and digestive comfort within 1-2 weeks of consistent daily use. For pets with more significant or long-standing digestive concerns, it may take 4-6 weeks of regular supplementation before the full benefit is apparent. Results can vary depending on the individual pet, diet, and any underlying factors your veterinarian has identified. Daily consistent use is key to maintaining the microbiome balance that Microflora Plus supports.
Microflora Plus is frequently used alongside other Herbsmith formulas and general wellness supplements. If your pet is on prescription medications or has a diagnosed health condition, it is best to consult your veterinarian before adding any new supplement to their routine. Your veterinarian can confirm compatibility based on your pet's full health picture and current medication regimen.
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