{"product_id":"k9-select-beef-flavored-3mg-melatonin-supplement-for-dogs-120-chewable-tablets","title":"K9 Select Beef-flavored 3mg Melatonin Supplement for Dogs (120 Chewable Tablets)","description":"\u003cdiv align=\"left\"\u003e\n\u003ch2 data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eK9 Select Beef Flavored Melatonin 3mg\u003c\/strong\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch5 style=\"text-align: left;\"\u003e\u003cspan style=\"text-decoration: underline;\"\u003e\u003cspan style=\"color: #a62b16;\"\u003e\u003cstrong\u003e\u003ca style=\"color: #a62b16;\" href=\"https:\/\/tcvmpet.com\/blogs\/news\/dog-cushings-disease-protocol\" target=\"_blank\" rel=\"noopener\"\u003eMore Help for Dogs Suffering from Cushing's Disease\u003c\/a\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/h5\u003e\n\u003cspan style=\"color: #000000;\"\u003e120 Chewable Tablets, 120 3 mg servings.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv align=\"left\"\u003e\u003cspan style=\"color: #000000;\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv align=\"left\"\u003e\n\u003ch4 class=\"p1\" style=\"text-align: left;\"\u003e\u003cb\u003eINGREDIENTS\u003c\/b\u003e\u003c\/h4\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #000000;\"\u003eActive Ingredients per tablet:  \u003c\/span\u003e\u003c\/strong\u003e\u003cspan style=\"color: #000000;\"\u003eMelatonin 3mg\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eInactive ingredients:\u003c\/strong\u003e \u003c\/span\u003e\u003cspan style=\"color: #000000;\"\u003eDicalcium phosphate, liver (desiccated and defatted), roast beef flavor, magnesium stearate, stearic acid, silicon dioxide. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eEach bottle contains 120 chewable tablets of 3 mg human-grade melatonin in a beef liver flavor that dogs love!\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4 data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eOur K9 Select brand melatonin supplements for dogs are carefully formulated to:\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul style=\"text-align: left;\"\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003ePromote a natural sleep-wake cycle\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eProvide natural hormone support\u003c\/li\u003e\n\u003cli\u003ePromote relaxation, calm and comfort\u003c\/li\u003e\n\u003cli\u003eSupport overall health – promote normal thirst and urination\u003c\/li\u003e\n\u003cli\u003eDaily use promotes normal skin and coat health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #000000;\"\u003eHow Melatonin Works\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eIn humans, dogs, and other animals, melatonin plays an important role in the regulation of the sleep-wake cycle. Melatonin is naturally produced by the body in the pineal system. In healthy animals, peak production of melatonin naturally occurs after sunset. Melatonin signals to the body both time of day and season (length of night). However natural production decreases as we and our pets age. This is one reason older people and pets find it difficult to get quality sleep or to sleep for as many hours as when we were younger.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch4 data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #000000;\"\u003eMelatonin Health Benefits\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eSupplementing with melatonin can be highly beneficial, as melatonin is a well-known antioxidant useful in regulating hormones and may reduce stress and anxiety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eMelatonin decreases sex hormone secretion, modulates aromatase activity, and inhibits cortisol production. It has also been shown in some animal models to\u003ca style=\"color: #000000;\" href=\"https:\/\/avmajournals.avma.org\/doi\/abs\/10.2460\/ajvr.72.5.675\" target=\"_blank\" rel=\"noopener\"\u003e inhibit androgen production and ovarian activity\u003c\/a\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eMelatonin’s anti-estrogenic properties have been extensively studied.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eMelatonin acts in \u003ca style=\"color: #000000;\" title=\"Physiological effects of Melatonin\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0301008208000348\" target=\"_blank\" rel=\"noopener\"\u003eseveral ways\u003c\/a\u003e to limit estrogen production and\/or \u003ca style=\"color: #000000;\" href=\"https:\/\/www.hilarispublisher.com\/open-access\/melatonininduced-oncostasis-mechanisms-and-clinical-relevance-2329-6771-S1-006.pdf\" title=\"Melatonin-induced oncostasis\" target=\"_blank\" rel=\"noopener\"\u003eactivities\u003c\/a\u003e, including by interfering with estrogen receptor activities, downregulating estrogen expression during transcription, reducing estrogen receptor sensitivity, and inhibiting the expression of key enzymes (like aromatase) involved in estrogen production. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eIn addition, melatonin has been shown not only to \u003ca style=\"color: #000000;\" href=\"https:\/\/academic.oup.com\/jcem\/article\/88\/1\/450\/2846096\" title=\"mt1 melatonin receptor inhibition of cortisol production\" target=\"_blank\" rel=\"noopener\"\u003einhibit cortisol itself\u003c\/a\u003e, but \u003ca style=\"color: #000000;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21332028\/\" title=\"melatonin-induced inhibition of ACTH\" target=\"_blank\" rel=\"noopener\"\u003ealso the chemical (ACTH)\u003c\/a\u003e that signals the adrenal gland to produce cortisol.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eStudies have shown melatonin can reduce symptoms of stress in canines, including refusal to eat, excessive pacing or panting, whimpering, and licking. Melatonin may also help reduce aggressive behavior in dogs. Because the body responds to stress by producing additional cortisol, the reduction in stress, anxiety and aggression that results from melatonin supplementation may have a secondary effect (beyond the direct effects noted above) of lowering cortisol levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ch4 align=\"left\" style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #000000;\"\u003eDirections for Dogs\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cdiv align=\"left\" style=\"text-align: left;\"\u003eThe University of Tennessee College of Veterinary Medicine recommends, and the late Dr. Jack Oliver, DVM, former Chairman of UTK’s Veterinary Endocrinology Department, recommended:\u003c\/div\u003e\n\u003cdiv align=\"left\"\u003e\n\u003cul data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\n\u003cli\u003e\u003cspan style=\"color: #000000; font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e3 mg of melatonin (1 tablet) every 12 hours for dogs under 30 lbs.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e6 mg of melatonin (2 tablets) every 12 hours for dogs over 30 lbs.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e1 mg of melatonin (you may cut the tablet in half) every 12 hours may be recommended for dogs 10 lbs. or less, or for those who want to give their dogs very low doses of melatonin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\" style=\"text-align: left;\"\u003e\u003cspan style=\"color: #000000;\"\u003eMelatonin may also help anxious dogs by reducing stress hormone levels. For this use, give 1 serving 30 minutes before stressful event.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan style=\"color: #000000;\"\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e Always consult your physician or veterinarian before giving melatonin to your dog. For treatment of dogs, you should not use a rapid release melatonin or a timed-release melatonin. Use only regular melatonin. All of our melatonin products fit these criteria.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cquillbot-extension-portal\u003e\u003c\/quillbot-extension-portal\u003e\u003c\/p\u003e","brand":"K9 Select","offers":[{"title":"Default Title","offer_id":39395654336582,"sku":"K9S3MGM120","price":20.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0021\/2110\/5457\/products\/K9_Select_Beef-flavored_3mg_Melatonin_Supplement_for_Dogs_120_Chewable_Tablets.jpg?v=1782244537","url":"https:\/\/tcvmpet.com\/products\/k9-select-beef-flavored-3mg-melatonin-supplement-for-dogs-120-chewable-tablets","provider":"TCVM Pet Supply","version":"1.0","type":"link"}